The best time to take medicine for heart disease patients is ______.

A．passengers can choose the flight time to adjust biological clocks
B．people may sleep at daytime for better biological clocks condition
C．shift workers can avoid their biological clock disorders
D．patients can get the best result by taking medicines at different time

A．reduces the toxic effects by decreasing the amount of medicine-taking
B．balances the effect of the medicine in accordance with humans' different functions in a day
C．allows patients to choose the time to take medicine as they like
D．patients should follow the time of taking medicine according to the paper instructions