单项选择题

The disease failed to ______ to the new drugs the doctor applied.

A．respond
B．correspond
C．answer
D．reply
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单项选择题
As long ago as the fourteenth century, an Englishman made ______ the discovery that people would rather pay large sums of money than have their life work destroyed.
A．distinct
B．substantial
C．noticeable
D．significant
单项选择题
In the past, it was believed that ______ was more prevalent among the poorer and less educated people, but that is not the case.
A．destination
B．depression
C．definition
D．destruction
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