TEXT A We sometimes think humans
are uniquely vulnerable to anxiety, but stress seems to affect the immune
defenses of lower animals too. In one experiment, for example, behavioral
immunologist Mark Laudenslager, at the University of Denver, gave mild electric
shocks to 24 rats. Half the animals could switch off the current by turning a
wheel in their enclosure, while the other half could not. The rats in the two
groups were paired so that each time one rat turned the wheel it protected both
itself and its helpless partner from the shock. Laudenslager found that the
immune response was depressed below normal in the helpless rats but not in those
that could turn off the electricity. What he has demonstrated, he believes, is
that lack of control over an event, not the experience itself, is what weakens
the immune system. Other researchers agree. Jay Weiss, a
psychologist at Duke University School of Medicine, has shown that animals who
are allowed to control unpleasant stimuli don’t develop sleep disturbances or
changes in brain chemistry typical of stressed rats. But if the animals are
confronted with situations they have no control over, they later behave
passively when faced with experiences they can control. Such findings reinforce
psychologists’ suspicions that the experience or perception of helplessness is
one of the most harmful factors in depression. One of the most
startling examples of how the mind can alter the immuue response was discovered
by chance. In 1975 psychologist Robert Ader at the University of Rochester
School of Medicine conditioned mice to avoid saccharin by simultaneously feeding
them the sweetener and injecting them with a drag that while suppressing their
immune systems caused stomach upsets. Associating the saccharin with
the stomach pains, the mice quickly learned to avoid the sweetener. In
order to extinguish this dislike for the sweetener, Ader reexposed the animals
to sac charin, this time without the drug, and was astonished to find that those
mice that had received the highest amounts of sweetener during their earlier
conditioning died. He could only speculate that he had so successfully
conditioned the rats that saccharin alone now served to weaken their immune
systems enough to kill them. The passage tells us that the most probable reason for the death of the mice in Ader’s experiment was that ______.
A.they had been weakened psychologically by the saccharin B.the sweetener was poisonous to them C.their immune systems had been altered by the mind D.they had taken too much sweetener during earlier conditioning