单项选择题

患者，女性，39岁，餐后3小时突觉上腹部刀割样剧痛，持续性，伴恶心入急诊，急诊护士查体：腹式呼吸消失，移动性浊音阳性，全腹压痛、反跳痛、肌紧张，上腹为甚。考虑为

A.胃十二指肠溃疡急性穿孔
B.胃溃疡出血
C.十二指肠溃疡出血
D.胃溃疡癌变
E.胆囊炎
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