In which year was aspirin first sold

A．Aspirin is the largest suicide drug.
B．The side effects of aspirin are largely recognized by its users.
C．The best way to take aspirin is to chew the tablets before swallowing them with water.
D．Aspirin was available in the United States during the 19th century.

A．The effectiveness and safety of aspirin.
B．The functions of aspirin.
C．The development and the effectiveness and side effects of aspirin.
D．The 20th century wonder drug -- aspirin.