Infections ’Speed Memory Loss’ Infections outside the brain may speed memory decline in Alzheimer’ s disease, UK researchers say. The Southampton University researchers studied 222 elderly people with Alzheimer’ s for six months, and they found that getting infections in places like the chest or urinary tract (尿道) could lead to higher level of an inflammatory (引发炎症的) protein called turnout necrosis factor (TNF) in the blood, and double memory loss. There were 110 of the 222 subjects who developed a total of 150 infections, in areas such as the chest, stomach and intestines (肠) and the urinary tract, which led to the production of TNF proteins. These are collectively known as acute systemic inflammation events (SIEs). Subjects with one or more SIEs during the six months follow - up had two times the rate of cognitive decline from their baseline score at the start of the study compared with those who had no SIE. And those patients who had high baseline levels of TNF and then suffered an SIE over the following six months had a 10 fold increase in the rate of cognitive decline compared to those who were SIE free. Dr Susanne Sorensen, Head of Research, Alzheimer’ s Society said: We know there might be a link between inflammatory processes and Alzheimer’ s but this is not yet fully understood. "In the meantime it’ s important that older people, people with dementia treat any infection seriously and seek medical help in time. "Professor Clive Holmes at the University of Southampton, who led the research, said they had looked at patients with mild, moderate and severe Alzheimer’s disease. "The worse the infection the worse the affect on the memory, but this is only an association at the moment. " One might guess that people with a more rapid rate of cognitive decline are more susceptible to infections or injury, but we found no evidence to suggest that people with more severedementia (痴呆) were more likely to have infections or injuries. "If further work proves that TNF is causing more brain inflammation it may be possible to use drugs that block TNF to help dementia sufferers. " Professor Holmes said although common illnesses like colds and slight wounds could also set up an inflammatory response in the body, the data from his study did not support the idea that even these could cause memory loss. What description is not agreeable to the first paragraph
A.UK researchers have studied people who had brain infections and found there is no connection between infections and memory lost. B.It is found that infections in the chest or urinary tract could lead to memory lost in people with Alzheimer’ s disease. C.UK researchers studied people with Alzheimer’ s disease and found the connection between infections and memory lost. D.TNF is a kind of inflammatory protein, the level of which can influence the memory of people with Alzheimer’ s diseas