Rats that eat high levels of a natural sugar known as fructose (果糖) seem to age faster than other rats-and the same could be true for people who eat too much sweet (67) food, Israeli researchers said. Fructose, found (68) in honey and fruit, is used widely in foods (69) from soft drinks to yogurt. But (70) its sweet taste is popular, the sugar could cause wrinkles and health problems, the researchers said. Dr. Moshe Werman and Boaz Levi of the Technion-Israel Institute of Technology (71) large amounts of fructose to laboratory rats. Writing in the Journal of Nutrition, they said the fructose-fed rats showed changes (72) the collagen (胶原质) of their skin and bones. Collagen, a fibrous protein found in connective tissue, bone and cartilage (软骨), basically holds the body together. The (73) of collagen is what causes sagging (松弛) and deep wrinkles in older people. The process affected, Werman’s team said, is known as "cross linking". "Too much cross-linking reduces elasticity and makes the skin (74) and rigid, and these are the conditions that encourage wrinkled skin," Werman said in a statement. He said the same could be true of people, (75) this has not been shown. "Americans are eating more and more (76) foods such as carbonated drinks, baked goods, canned fruits jams and dairy products that (77) fructose," Werman said. Other studies have shown that (78) fructose intake can affect how the body (79) glucose(葡萄糖) and increases insulin(胰岛素) resistance-which can (80) be important measures of the (81) toward diabetes. The rats Werman worked (82) were fed much more than the (83) adult person might eat in a day, which is standard in such (84) The rats were fed 12.5 grams of fructose per kg (2.2 pounds) of weight every day for a year. To (85) , a person weighing 154 pounds (70kg) who drinks a quart (liter) of cola (86) about 60 grams of fructose, or 0.8 grams per kg of body weight.