填空题

It is a timeworn sign of old age and frailty. Yet arthritis often (1)______ the young. (1) ______ This disease of the body also has a (2)______ impact on the mind. (2) ______ "got very (3)______ I couldn’t sleep. (3) ______ When pain is (4)______ like that, it changes your personality. (4) ______ And it affected everyone around me, " says Nora Baldner, who had arthritis in both hips. "I" d pour (5)______ milk on my kids’ cereal because I didn’t want to walk to the back of the supermarket where the real milk was." (5) ______ Joint problems are now hurting and crippling 43 million Americans, and they’re more (6)______ than cancer or diabetes. (6) ______ The most common form, osteoarthritis, affects about 21 million. Rheumatoid arthritis, another common type, hits slightly more than 2 million. (There are 95 or so other forms, often affecting fewer people.) And the numbers are going up (7)______. (7) ______ By 2025, the total is expected to top (8)______ million, (8) ______ as an obese population pounds more heavily on its joints and an active generation of baby (9) ______ grinds them down. (9) ______ What’s worse, these people will be fighting the disease without medicines that had become staples of treatment: The drugs Vioxx and Bextra have just been yanked off the market because they appear to (10)______ the risk of heart disease, (10) ______ and that same shadow of fear has been cast over remaining drugs like Celebrex and even ibuprofen—a medicine that had already worded doctors because heavy use can cause bleeding in the stomach.